Written and medically reviewed by Alonso Martin, MD
Licensed physician and Founder & Medical Director of BODYWELLE. Dr. Martin earned his MD from Michigan State University and completed his Family Medicine residency at the University of California, Irvine.
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Last reviewed: August 07, 2026
Is EBOO therapy safe? For most healthy adults who are properly screened, it generally is, provided the procedure is performed in a medical setting with appropriate oversight. EBOO, short for extracorporeal blood oxygenation and ozonation, circulates your blood through a filtration, ozonation, and ultraviolet system before returning it to the body. Because it works directly with your blood, its safety depends primarily on candidate selection and technique rather than on the therapy in the abstract.
I am Dr. Alonso Martin, and my practice at BODYWELLE in Miami Beach is grounded in longevity and integrative medicine. When a patient asks me about EBOO, I consider it my responsibility to be clear about both its potential and its limits. What follows is a direct account of how EBOO works, what its risks are, and who is and is not a candidate.

The Benefits of EBOO Therapy, Weighed Against the Risks
- EBOO therapy circulates your blood through a filter, medical ozone and oxygen, and UV light, then returns it.
- For healthy, properly screened patients, EBOO is generally safe in a medical setting.
- Most side effects are mild, such as temporary fatigue or soreness at the IV site.
- EBOO is not right for everyone, including people with certain bleeding disorders.
- A medical consultation is what determines whether EBOO therapy is safe for you.
What Is EBOO Therapy?

EBOO stands for extracorporeal blood oxygenation and ozonation. It is a method of treating your blood outside the body and then returning it to circulation. A 1-liter volume of blood over a session is routed through a sealed medical-grade circuit, where it passes through a blood filtration membrane, is mixed with medical-grade ozone and oxygen, and is then treated with ultraviolet light.
That three-part design is what separates EBOO from a standard ozone treatment, which works with much smaller volumes. The combination is intended to support circulation, oxygen delivery, immune function, and the body’s natural healing and detoxification, all at the level of the blood itself. EBOO is sometimes called ozone dialysis, although it is not dialysis in the kidney sense.
According to a peer-reviewed review published in Redox Report, EBOO was developed to allow a substantially larger volume of blood to be exposed to an oxygen-ozone mixture through extracorporeal circulation than conventional ozone autohemotherapy.
How Safe Is EBOO Therapy?
For the right candidate, EBOO has a reassuring safety profile when it is administered correctly. The blood stays within a sealed, medical-grade circuit, the ozone is precisely produced and dosed, and the process is monitored from start to finish. Most patients tolerate it well and return to normal activity the same day.
That said, EBOO is only as safe as the conditions under which it is performed. Real safety comes from three things working together: appropriate patient selection, sterile and properly calibrated equipment, and trained clinicians who monitor you throughout. Remove any one of those and the risk profile changes. This is why I am cautious about EBOO offered in non-medical settings, where screening and oversight may be thin.
What Happens During EBOO Treatment?
Understanding the steps tends to ease most concerns. An EBOO session at my clinic looks like this:
- A small intravenous line is placed, typically in each arm, one to draw blood and one to return it
- Your blood is gently and continuously circulated through the filtration and ozonation system
- The blood is filtered, blended with medical grade ozone and oxygen, and passed under ultraviolet light
- The treated, ozonated blood is returned to your body in a continuous loop
- You rest comfortably throughout, and the session usually lasts about 60 to 75 minutes
There is no anesthesia and no surgical incision. Afterward, I ask patients to hydrate well and keep activity light for the rest of the day. The treatment process is meant to be calm and uneventful, which in a medical procedure is exactly what you want.
Possible Side Effects and Risks of EBOO
No medical treatment is free of risk, and I would not trust anyone who told you otherwise about EBOO. For screened patients, though, the effects are usually mild and short-lived.
Common, minor side effects include:
- Temporary fatigue or low energy after a session
- Mild soreness, bruising, or tenderness at the IV site
- Brief lightheadedness as your body adjusts
More serious risks are rare but real, which is precisely why setting and technique matter. Because EBOO works with circulating blood and a gas, improper handling carries a small risk of vascular irritation or, very rarely, an air embolism. In a properly equipped clinic with trained staff and calibrated equipment, these events are uncommon. I mention them not to alarm you, but because honest safety information is part of informed consent.
Who Should Consider EBOO?
EBOO is best understood as a wellness and longevity therapy rather than a medical treatment for a specific disease. The patients who tend to benefit are generally healthy adults who want to support circulation, energy, the immune system, and overall health, or who are focused on recovery and performance. Many patients come to me already doing the basics well and looking for a deeper, blood-level layer of support, including support for the body’s balance against oxidative stress and chronic inflammation.
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When EBOO May Not Be the Right Fit
EBOO is not appropriate for everyone, and screening exists to catch that. I generally advise against EBOO, or proceed only with extra caution and coordination, for people who:
- Have bleeding or clotting disorders such as hemophilia
- Are pregnant
- Have certain cardiovascular or respiratory conditions
- Are undergoing chemotherapy or other active cancer treatment without oncology clearance
- Have G6PD deficiency, an enzyme condition that ozone can affect
This is not a complete list, and it is not a substitute for an evaluation. It is simply why a thorough medical history matters before anyone treats your blood. If EBOO is not right for you, I will say so, and often there are gentler options that may suit your goals better.

Why Choose BODYWELLE for EBOO in Miami Beach?
If you decide EBOO is right for you, where you have it done matters as much as the decision itself. At BODYWELLE, EBOO is delivered as part of a physician-led program under my oversight, with medical-grade equipment and trained clinical staff. Every case begins with a consultation and a review of your health history.
I also place EBOO within a larger picture. It is one tool within an integrative medicine approach that may include IV therapy, peptides, and other longevity strategies, chosen around your goals rather than a fixed menu. That context is part of what keeps the therapy both effective and safe.
Schedule an EBOO Consultation in Miami Beach, FL
Deciding whether EBOO is right for you starts with an evaluation. Request an appointment at BODYWELLE in Miami Beach, and we can review your health history and goals together at your consultation.
Frequently Asked Questions About EBOO Therapy Safety
Can EBOO therapy make you feel tired afterward?
Yes, and it is usually nothing to worry about. Some patients feel mild fatigue or low energy after a session as the body processes the effects of treatment. This typically passes within a day, and staying well hydrated helps.
What makes EBOO different from regular IV therapy?
Standard IV therapy delivers fluids, vitamins, or nutrients into your bloodstream. EBOO does something different. It circulates your blood out of the body through a filtration, ozonation, and ultraviolet system, then returns it. It is a more involved procedure, which is also why it calls for closer medical oversight.
Can patients with health conditions receive EBOO therapy?
It depends entirely on the condition. Some health issues, such as bleeding disorders, pregnancy, or active cancer treatment, may make EBOO inappropriate or require special clearance. This is exactly what the pre-treatment evaluation is for. Never assume, in either direction, without a medical review.
How do I know if EBOO is safe for me?
The honest answer is that you find out through a consultation. A review of your medical history, current medications, and health goals is what tells me whether EBOO therapy is safe and worthwhile for you specifically. Safety here is individual, not one-size-fits-all.
About the Author
Dr. Alonso Martin, MD, leads BODYWELLE in Miami Beach, a longevity and integrative medicine practice where EBOO is offered under his supervision. He came to wellness and aesthetic medicine by way of neuroscience and family medicine, and he is known for a conservative, screening-first approach to advanced therapies. His view is a simple one. A treatment is only worth offering when it is both right for the individual in front of him and delivered safely.
